Fig. 3. G-CSF and SCF improved functional outcome at 14days post HI.
The combination treatment group (G-CSF + SCF) showed significant improvement in neurological function according to (a) Modified Garcia test, where sensori-motor function was evaluated. Vehicle and SCF groups scored significantly worse on the 21 score scale system when compared to sham while the G-CSF+SCF treatment group showed significant improvement compared to vehicle and (b) Foot fault test, which shows the percentage of foot faults of the contralateral forelimb. The results show that ischemia-induced foot slips were significantly reduced by treatment with SCF and G-CSF+SCF (Data represent +/− SEM; *p<0.05 versus sham, #p<0.05 versus vehicle).