Table 1. List of the top miR-210 predicted targets significantly downregulated in the pmiR-210 A549 cell line.
| Symbol | Gene ID | AVEEXPR | LOGFC | Description |
|---|---|---|---|---|
| CORO1C | 23603 | 11.68 | −0.44 | Coronin, actin binding protein, 1C |
| DIMT1L | 27292 | 12.13 | −0.89 | DIM1 dimethyladenosine transferase 1-like |
| ELFN2 | 114794 | 9.27 | −0.61 | Extracellular leucine-rich repeat and fibronectin type III domain containing 2 |
| ENOX2 | 10495 | 9.65 | −0.54 | Ecto-NOX disulfide-thiol exchanger 2 |
| FGFRL1 | 53834 | 8.56 | −0.75 | Fibroblast growth factor receptor-like 1 |
| GPD1L | 23171 | 9.58 | −0.55 | Glycerol-3-phosphate dehydrogenase 1-like |
| INF2 | 64423 | 10.78 | −0.62 | Inverted formin, FH2 and WH2 domain containing |
| ISCU1/2 | 23479 | 13.06 | −0.58 | Iron-sulfur cluster scaffold homolog |
| MITF | 4286 | 9.84 | −0.52 | Microphthalmia-associated transcription factor |
| NDUFA4 | 4697 | 14.87 | −0.58 | NADH dehydrogenase (ubiquinone) 1αsubcomplex, 4, 9 kDa |
| SDF2 | 6388 | 10.63 | −0.61 | Stromal cell-derived factor 2 |
| SDHD | 6392 | 11.06 | −0.46 | Succinate dehydrogenase complex, subunit D, integral membrane protein |
| ST6GAL2 | 84620 | 10.20 | −0.57 | ST6 β-galactosamide α-2,6-sialyltranferase 2 |
| TMEM20 | 159371 | 7.98 | −0.49 | Transmembrane protein 20 |
| TNPO1 | 3842 | 9.69 | −0.41 | Transportin 1 |
| VAMP7 | 6845 | 11.21 | −0.78 | Vesicle-associated membrane protein 7 |
Sixteen of the miR-210 predicted transcripts selected using the bioinformatics tool miRonTop (http://www.microarray.fr:8080/miRonTop/index) are listed. The Target Prediction Tool used was TargetScan. Cutoff values for selection are equal to 7 for logarithm (base 2) of the average intensity (AveExpr), to 0.4 for the logarithm (base 2) of the ratio (pmiR-210/pmiR-Ctr) (logFC) and 0 for the B-value. Gene ID: corresponds to NCBI Gene ID (http://www.ncbi.nlm.nih.gov/gene)