Figure 2.

In vitro anticancer effects of amino endoperoxides and their derivatives. (a, b) Percentage of Annexin V positive (apoptotic) cells in adhered (a) and suspended (b) MDA-MB-231 and MCF-10A cells treated with indicated amino endoperoxide compounds and their derivatives under indicated concentrations for 0.5 h. See Supplementary Figure S2 for detailed FACS. Experiments were independently performed three times with at least three replicates of each sample. The concentration 0 indicates vehicle control. Error bars: S.E.M. Comparison was performed against cognate vehicle controls. *P<0.05, **P<0.01; ***P<0.001