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Blocking synaptic receptors results in resistance to OGD. DIV 14 neurons were first treated with bicuculline plus MK801 for 2βmin, washed extensively, and subjected to a 75-min OGD. (a) Cell death was determined 20βh later by DAPI staining. (b) Neuronal extracts were harvested immediately after OGD, and analyzed for p-CREB, p-AKT, and activated caspase-3 by western blot. β*' denotes P<0.05 when compared with the control; β#' denotes P<0.05 when compared with the OGD group
