TABLE III.
Patient and tumour characteristics and initial treatment in patients receiving and not receiving an adjuvant taxane
| Characteristic |
Adjuvant taxane
|
p Valueb | |
|---|---|---|---|
| Yesa | No | ||
| Patients (n) | 30 | 92 | |
| Nodal status [n (%)] | |||
| Negative | 3 (10.0) | 27 (29.3) | |
| Positive | 26 (86.7) | 45 (48.9) | 0.007 |
| Unknown | 1 (3.3) | 20 (21.7) | |
| Positive nodes [n (%)] | |||
| 0 | 3 10.0 | 27 29.3 | 0.02c |
| 1–3 | 10 (33.3) | 26 (28.3) | |
| 4–9 | 8 (26.7) | 11 (12.0) | |
| 10+ | 7 (23.3) | 7 (7.6) | |
| Grade [n (%)] | |||
| 1 | 4 (13.3) | 5 (5.4) | |
| 2 | 5 (16.7) | 45 (48.9) | |
| 3 | 21 (70.0) | 35 (38.0) | 0.002c |
| Unknown | 0 (0.0) | 7 (7.6) | |
| her2 status [n (%)]d | |||
| Positive | 2 (6.7) | 8 (8.7) | 0.67 |
| Negative | 28 (93.3) | 79 (85.9) | |
| Unknown | 0 (0.0) | 5 (5.4) | |
| er status [n (%)]d | |||
| Positive | 16 (53.3) | 78 (84.8) | |
| Negative | 14 (46.7) | 12 (13.0) | |
| Unknown | 0 (0.0) | 2 (2.2) | |
| Initial radiotherapy [n (%)] | |||
| None | 7 (23.3) | 45 (48.9) | |
| Breast and chest wall only | 2 (6.7) | 21 (22.8) | |
| Breast and chest wall plus regional nodes | 21 (70.0) | 26 (28.3) | |
| Initial hormonal therapy [n (%)] | |||
| Yes | 11 (36.7) | 59 (64.1) | 0.008 |
| No | 19 (63.3) | 33 (35.9) | |
a
Includes patients who received at least 1 cycle of a taxane.
b
Calculated on known values only.
c
By exact chi-square test (when expected cell counts are not met for chi-square test in non-2×2 tables).
d
At initial diagnosis, or if unknown at initial diagnosis, then at recurrence.
her2 = human epidermal growth factor receptor 2; er = estrogen receptor.