Table 2.
Logistic regression analysis
| Biomarker | AUC | 95% confidence interval
|
|
|---|---|---|---|
| Sensitivity (%) | Specifcity (%) | ||
| FTH1 | 0.686 | 0.812 | 0.561 |
| hnRNPF | 0.725 | 0.842 | 0.608 |
| CA 15-3 | 0.792 | 0.691 | 0.894 |
| FTH1 + hnRNPF | 0.816 | 0.911 | 0.720 |
| FTH1 + CA 15-3 | 0.834 | 0.851 | 0.927 |
| hnRNPF + CA 15-3 | 0.862 | 0.874 | 0.910 |
| FTH1 + hnRNPF + CA 15-3 | 0.931 | 0.893 | 0.938 |
Notes: AUC indicates diagnostic accuracy of biomarkers. The highest AUC is 1.
Abbreviations: AUC, area under the curve; FTH1, ferritin heavy chain; hnRNPF, heterogeneous nuclear ribonucleoproteins F.