Table 2.
Demographic and MRI measures for schizophrenia patients, non-psychotic relatives of patients, C (community comparison) probands, and non-psychotic relatives of C probands
| Schizophrenia patients |
Patient relatives |
C probands | Relatives of C probands |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Siblings | Parents | Siblings | Parents | |||||||||
|
|
|
|
|
|
|
|||||||
| (N=48) |
(N=24) |
(N=42) |
(N=27) |
(N=38) |
(N=39) |
|||||||
| Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | |
| Demographic measures | ||||||||||||
| Age (years)a | 31.8 | 9.0 | 31.8 | 13.3 | 55.6 | 9.6 | 26.4 | 7.1 | 26.9 | 9.4 | 56.1 | 8.0 |
| Handedness (L/R) | 4/44 | 2/22 | 3/39 | 2/25 | 1/37 | 3/36 | ||||||
| Gender (M/F)a | 35/13 | 13/11 | 14/28 | 19/8 | 18/20 | 17/22 | ||||||
| MRI measures (cm3) | ||||||||||||
| Brain volumea | 1427.3 | 135.9 | 1408.7 | 153.6 | 1329.8 | 148.7 | 1398.4 | 114.5 | 1418.0 | 164.7 | 1381.8 | 152.8 |
| Gray matter volumea,b | 667.1 | 42.4 | 677.0 | 42.0 | 625.8 | 42.4 | 707.3 | 38.1 | 709.0 | 41.3 | 618.7 | 45.0 |
| White matter volumea,b | 537.5 | 35.0 | 532.8 | 39.7 | 544.6 | 37.9 | 517.0 | 24.1 | 511.5 | 34.9 | 536.9 | 34.1 |
a
Indicates significant group difference.
b
Denotes that volumes were corrected for total brain volume, sex and age.