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. Author manuscript; available in PMC: 2013 Apr 3.
Published in final edited form as: Cancer Prev Res (Phila). 2011 Jun 16;4(9):1436–1448. doi: 10.1158/1940-6207.CAPR-10-0346

Table 1b.

Mammary tumor histopathology in DMBA-exposed wildtype (WT) and Brca1+/− mice fed a control or genistein supplemented AIN93G diet during prepuberty

Benign Malignant Tumor grade Mitotic Index
Group Adenoma Adeno-carcinoma Carcinoma (Other) Low High (mean±SEM)
WT control 1 (10%) 6 (60%) 3(30%) 3(33%) 6(67%)a 5.0±0.8a
WT genistein 1 (20%) 1 (20%) 3 (60%) 3(75%) 1(25%)b 1.4±1.1b
Brca1+/− control 1 (8%) 9 (75%) 2 (17%) 3(27%) 8(63%)a 2.1±0.7b
Brca1+/− genistein 2 (20%) 4 (40%) 4 (40%) 3(37%) 5(63%)a 2.0±0.8b

Values within a column which are marked with a different letter are significantly different from each other, p<0.05.