Table 2. Baseline Demographic and Clinical Characteristics of patients with and without Serious Adverse Drug Reactions (SADR), N = 1390.
| No Serious ADR n = 1307 Mean (±SD) | Serious ADR n = 83 Mean (±SD) | P value (CI 95%) | |||
| Age (years) | n = 1292* 36.3 (10.6) | n = 83 37.3 (11.3) | 0.425 | ||
| Pre-Treatment Weight (kg) | n = 1171* 50.9 (10.5) | n = 72* 51.2 (11.3) | 0.747 | ||
| Number | (%) | Number | (%) | ||
| Male | n = 1304* 797 | (61.1) | 44 | (53.0) | 0.164 |
| HIV-infected | 504 | (38.6) | 40 | (48.2) | 0.083 |
| MDR Classification | 0.950 | ||||
| New MDR TB, Unknown Previous TB | 35 | (2.7) | 2 | (2.4) | |
| New MDR-TB, No Previous TB | 88 | (6.7) | 6 | (7.2) | |
| New MDR-TB, Previous TB | 1184 | (90.6) | 75 | (90.4) | |
| Radiographic Findings Total | 935* | 58* | |||
| Unilateral Disease | 150 | (16.0) | 5 | (8.6) | |
| Bilateral Disease | 785 | (84.0) | 53 | (91.4) | 0.189 |
| Smear status Positive | n = 1164* 806 | (69.2) | n = 74* 55 | (74.3) | 0.435 |
| Culture status Positive (at treatment initiation) | n = 1226* 1051 | (85.7) | n = 75* 64 | (85.3) | 0.866 |
| Treatment Outcome | 0.406 | ||||
| Cure | 349 | (26.7) | 27 | (32.5) | |
| Completed | 313 | (24.0) | 21 | (25.3) | |
| Successfully treated | 662 | (54.3) | 48 | (57.8) | |
| Failure | 115 | (8.8) | 6 | (7.2) | |
| Default | 278 | (21.3) | 11 | (13.3) | |
| Died | 252 | (19.3) | 18 | (21.7) | |