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A. PAI and tPA mRNA level by RT-PCR.B. PAI and tPA mRNA level by real time RT-PCR. C. PAI and tPA protein levels by western blot. Tryptase increased tPA expression and inhibited PAI-1 expression at the mRNA and protein level in bEnd.3 cells. *P<0.01 vs. the mock and blank groups (n = 3).
