Table 2. Univariate and Multivariate Analysis of Different Prognostic Features in 169 Patients with Ovarian Carcinoma.
| Variable | Univariate Analysis* | Multivariate Analysis† | ||||
| All Cases | Mean Survival (Months) | Median Survival (Months) | P Value | HR (95% CI) | P Value | |
| Age at surgery (years) | 0.797 | |||||
| ≤50.8‡ | 83 | 80.4 | 66.0 | |||
| >50.8 | 86 | 84.6 | NR | |||
| Histological type | 0.421 | |||||
| Serous | 113 | 70.5 | 72.0 | |||
| Mucinous | 21 | 82.6 | 81.0 | |||
| Endometrioid | 7 | 132.4 | NR | |||
| Clear cell | 7 | 102.8 | NR | |||
| Undifferentiated | 21 | 35.2 | NR | |||
| Histological grade (Silveberg) | 0.020 | 0.987 (0.629–1.548) | 0.955 | |||
| G1 | 29 | 105.6 | 136.0 | |||
| G2 | 100 | 77.6 | 66.0 | |||
| G3 | 40 | 50.0 | 29.0 | |||
| pT status | 0.005 | 1.246 (0.804–1.933) | 0.325 | |||
| pT1 | 47 | 110.2 | NR | |||
| pT2 | 32 | 84.9 | NR | |||
| pT3 | 90 | 66.6 | 37.0 | |||
| pN status | 0.000 | 2.121 (1.219–3.689) | 0.008 | |||
| pN0 | 83 | 96.6 | 136.0 | |||
| pN1 | 86 | 55.7 | 39.0 | |||
| pM status | 0.000 | 1.228 (0.335–4.503) | 0.757 | |||
| pMX | 146 | 91.1 | 136.0 | |||
| pM1 | 23 | 23.4 | 13.0 | |||
| FIGO stage | 0.000 | 2.965 (1.213–7.244) | 0.017 | |||
| I | 30 | 134.2 | NR | |||
| II | 20 | 113.7 | NR | |||
| III | 96 | 71.2 | 45.0 | |||
| IV | 23 | 23.4 | 13.0 | |||
| Beclin 1expression | 0.000 | 0.489 (0.273–0.909) | 0.013 | |||
| Low | 94 | 57.8 | 34.0 | |||
| High | 75 | 110.2 | 136.0 | |||
| Bcl-xl expression | 0.028 | 1.894 (0.859–3.556) | 0.147 | |||
| Low | 58 | 84.2 | NR | |||
| High | 111 | 74.5 | 34.0 | |||
*
Log-rank test; †Cox regression model; ‡Mean age; HR indicates hazards ratio; CI indicates confidence interval; NR indicates not reached; FIGO indicates International Federation of Gynecology and Obstetrics.