Table 2. Diversity of potassium channel toxins (KTxs) from scorpion venom.

Classification	Gene Structure	3-D Fold	Activity
α-KTx subfamily	One intron in the signal peptide	CSα/β	Kv1, hERG, SKCa, BKCa, IKCa effectors
β-KTx subfamily	One intron in the mature peptide or two introns in the signal peptide	CSα/β	Kv1.3 effectors, antimicrobial and anti-malaria
γ-KTx subfamily*	One intron in the signal peptide	CSα/β	hERG effectors
κ-KTx subfamily*	One big intron in the signal peptide	CSα/α	Kv1.3 effectors
δ-KTx subfamily*	Two introns in the mature peptide	Kunitz-type	Kv1.3 effectors and Trypsin inhibitors

^*The genomic organization of this subfamily was reported firstly in this work.