Table 5. Improvement in Health-Related Quality of Life and Satisfaction after Knee Replacement: A Comparison Between Patients with Mild to Moderate and Severe Radiographical Pre-Operative Osteoarthritis.

SF36 Sub-Scale	Kellgren Grade 0–2:Probability of Achieving a MCID (95%CI)	Kellgren Grade 3+4:Probability of Achieving a MCID (95%CI)	Kellgren Grade 0–2 VS Kellgren Grade 3+4:Adjusted Odds Ratio (95%CI)	P-value
Physical Functioning	5/22∶22.7% (10.1–43.4)	105/191∶55.0% (47.9–61.9)	5.44 (1.45–20.3)	0.01
Role-Physical	9/22∶40.9% (23.3–61.3)	88/191∶46.1% (39.2–53.2)	1.46 (0.49–4.32)	0.50
Bodily Pain	15/22∶68.2% (47.3–83.6)	136/191∶71.2% (64.4–77.2)	1.15 (0.32–4.16)	0.83
General Health	9/22∶40.9% (23.3–61.3)	122/191∶63.9% (56.9–70.4)	3.56 (1.23–10.4)	0.02
Vitality	8/22∶36.4% (19.7–57)	86/191∶45.0% (38.1–52.1)	1.09 (0.35–3.44)	0.88
Social Functioning	7/22∶31.8% (16.4–52.7)	98/191∶51.3% (44.3–58.3)	2.84 (0.87–9.32)	0.08
Role Emotional	6/22∶27.3% (13.2–48.2)	41/191∶21.5% (16.2–27.8)	0.85 (0.26–3.02)	0.85
Mental Health	8/22∶36.4% (19.7–57)	79/191∶41.4% (34.6–48.4)	2.79 (0.70–11.2)	0.15
NRS Satisfaction >8	9/22∶40.9% (23.3–61.3)	116/191∶60.7% (53.7–67.4)	2.25 (0.78–6.52)	0.14

Odds Ratios >1 indicate a higher probability of achieving a Minimal Clinically Important Difference in HRQoL after THR in patients with Kellgren Grade 3+4, compared to Grade 0–2.

The odds ratios adjusted for age, sex, Charnley Comorbidity Classification and BMI and stratified for quartiles of follow-up.