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. 2013 Apr 3;8(4):e60785. doi: 10.1371/journal.pone.0060785

Figure 6. D-Cycloserine (DCS) rescues contextual fear conditioning deficit in GluD1 KO.

Figure 6

WT and GluD1 KO mice were intraperitoneally injected with saline or DCS (30 mg/kg) 30 min prior to contextual fear conditioning (n = 5–7 for each group). DCS administration in GluD1 KO significantly enhanced percent freezing during the post-test (two-way ANOVA, drug F(1, 20) = 18.97, P = 0.0003; genotype F(1, 20) = 9.616, P = 0.0056; interaction F(1, 20) = 4.424, P = 0.0483). Data are presented as mean ± SEM. * represents P< 0.05.