Figure 1.
Magnitude and time course of cocaine-like discriminative stimulus produced by the training dose of 0.32 mg/kg cocaine in rhesus monkeys (n=5). Effects of saline tests are also shown for comparison. Top Ordinate: percent cocaine-appropriate responding. Bottom Ordinate: rates of responding in responses per second. Abscissae: time in min after administration (log scale). Symbols above “S” and “C” represent the group averages SEM for all training sessions preceding test sessions when the saline- and cocaine-associated keys were correct, respectively. Filled symbols represent statistical significance (p < 0.05) within a given time point compared to experimental sessions when saline was administered (dotted line).