Figure 5.
EC50 values for (+)-phenmetrazine (Panel A) and (+)-phendimetrazine (Panel B) as a function of time (min) after phenmetrazine or phendimetrazine administration in rhesus monkeys. EC50 value in nM (log scale). Abscissae: time in min after administration of phenmetrazine (open circles) or phendimetrazine (half-filled circles) (log scale). EC50 values were only calculated in the presence of a significant correlation; see Supplemental Tables 2 and 3 for correlation results. All points show mean data from 5 monkeys.