Table 1.
N | % Females | % Socioeconomic deprivationa | BMIb | Mean TL (s.e.) at age 5c | Mean TL (s.e.) at age 10c | % Telomere lengtheningd | |
---|---|---|---|---|---|---|---|
Cumulative exposure | |||||||
None | 128 | 46.9 | 30.5 | 17.0 | 1.11 (0.04) | 0.99 (0.03) | 16.4 |
1 | 69 | 53.6 | 36.2 | 18.4 | 1.04 (0.06) | 0.95 (0.03) | 17.4 |
2+ | 39 | 48.7 | 66.7 | 17.6 | 1.04 (0.07) | 0.84 (0.05) | 17.9 |
Domestic violence | 40 | 60 | 65 | 18.3 | 1.09 (0.07) | 0.91 (0.05) | 27.5 |
Bullying victimization | 57 | 50.9 | 50.9 | 17.9 | 1.02 (0.06) | 0.90 (0.04) | 17.5 |
Physical maltreatment | 63 | 49.2 | 47.6 | 17.9 | 1.03 (0.06) | 0.88 (0.04) | 14.3 |
Total sample | 236 | 49.2 | 38.1 | 17.5 | 1.08 (0.03) | 0.96 (0.02) | 16.9 |
Original cohort | 2232 | 51.1 | 33.2 | 17.4 | Not applicable | Not applicable | Not applicable |
Abbreviations: BMI, body mass index; TL, telomere length.
Socioeconomic deprivation was constructed from a standardized composite of household income, parents’ highest education and parents’ highest occupational grade. Deprivation was defined as the lowest tertile of the distribution in the entire cohort.
BMI was constructed from parents’ reports of children’s height and weight, and computed as weight (kg)/(height (m2)).
Mean TL at ages 5 and 10 years adjusted for sex, socioeconomic deprivation and BMI at age 10 years.
Defined as >15% increase in TL.