Figure 2. Body weight, plasma lipids, B1a and other lymphocytes unchanged in ApoE^−/− mice treated with anti-BAFFR antibody.

A) Body weights, (B) Plasma lipids and (C) Peritoneal CD22⁺CD5⁺ B1a cells. (D) Peritoneal CD22⁺, CD5⁺ B1a B cells identified by FACS analysis. Red circle represents CD22⁺ CD5⁺ B1a cells (E) CD4⁺, CD8⁺, NK1.1⁺ (NK), NK1.1⁺ TCRβ⁺ (NKT) and CD4⁺ CD25⁺ foxp3⁺ regulatory T cells (T-reg) in spleens. n = 7–9 mice per each group □ control IgG treated mice; ▪ BAFFR-antibody treated mice.