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Nuclear β-catenin expression in brain metastases of adenocarcinomas of the lung (IHC): examples of the different nuclear β-catenin patterns. Nuclear β-catenin expression was classified into four groups: 0 = 0 %, 1+ = 1–25 %, 2+ = 25–50 % and 3+ > 50 % of the tumor cells with positive nuclear staining. Cytoplasmic and membrane staining did not enter the grading scheme
