Figure 2.

Maturation of adult-born DGCs. Critical time points over a period of several weeks are indicated within the purple bar. (Top) The morphological maturation of dendritic arbors of adult-born DGCs (adapted from Esposito et al., 2005). Axonal arbor development is not shown. (Bottom) Summary of reported findings during the maturation of adult-born DGCs. Each characteristic is listed to the left with references from which the timeline is depicted cited to the right. Black indicates the developmental age when the defined characteristic is indistinguishable between immature and mature DGCs (see primary literature for the specific time points that were included in each experiment). Ri, input resistance; g Kir, inward rectifier potassium conductance; DGCs, dentate granule cells; LTP, long-term potentiation; EC, entorhinal cortex. ML, molecular layer; GCL, granule cell layer; SGZ, sub-granular zone.