Table 2.
Comparison of the 1987 ACR RA and 2010 ACR/EULAR Classification Criteria for RA
1987 ACR classification criteria | 2010 ACR/EULAR classification criteria | |
---|---|---|
1) Morning stiffness >1 h | Who should be tested? Patients with ≥1 swollen joint consistent with synovitis not better explained by another disease. If the patient meets these initial criteria with a score of ≥6/10, he or she can be classified as having “definite RA”: | |
2) Arthritis of ≥3 joint areas | A. Joint involvement* | |
3) Hand arthritis | 1 large joint | 0 |
4) Symmetric arthritis | 2–10 large joints | 1 |
5) Nodules | 1–3 small joints | 2 |
6) Elevation of rheumatoid factor | 4–10 small joints | 3 |
7) Radiographic changes | >10 joints (at least 1 small) | 5 |
Findings 1–4 must be present for ≥6 weeks. Arthritis must be observed by a physician. | B. Serology (at least 1 test needed) | |
Negative RF and ACPA | 0 | |
Low positive RF or ACPA | 2 | |
High positive RF or ACPA** | 3 | |
C. Acute-phase reactants (at least one test needed) | ||
Normal CRP and ESR | 0 | |
Abnormal CRP or ESR | 1 | |
D. Duration of symptoms | ||
<6 weeks | 0 | |
≥6 weeks | 1 |
Categories of joint distribution are classified according to the location and number of involved joints, with placement into the highest category possible based on the pattern of joint involvement.
High positive is equivalent to >3 times the upper limit of normal based on the reference range of the laboratory that assesses the biomarker