Figure 1.

Salivary melatonin profiles of four patients with asymptomatic inflammatory bowel disease. Each patient’s habitual sleep times are represented by a black rectangle. Patients stopped consuming alcohol and caffeine three days before the melatonin assessment. Patient 1 had ulcerative colitis and was taking buspirone and sulfasalazine. Patient 2 had Crohn’s disease and was taking mercaptopurine, mesalamine, and risedronate sodium. Patient 3 had Crohn’s disease and was taking mesalamine only. Patient 4 had Crohn’s disease and was taking azathioprine and omeprazole.