Table 5.
Frequency of Human Leukocyte Antigen Haplotype Frequencies in the Nevirapine-Hypersensitive and -Tolerant Cohorts
| Hypersensitive (n = 116) |
Tolerant (n = 153) |
|||
|---|---|---|---|---|
| Frequency | Counts | Frequency | Counts | |
| B|C Haplotype | ||||
| 53:01:01|04:01 | 0.121 | 26 | 0.039 | 12 |
| 44:03|04:01 | 0.069 | 16 | 0.059 | 18 |
| 35:01|04:01 | 0.026 | 6 | 0.023 | 7 |
| 15:10|04:01 | 0.013 | 3 | 0.006 | 2 |
| 58:02|04:01 | 0.004 | 1 | ||
| 15:03|04:01 | 0.004 | 1 | ||
| 37:01:01|04:01 | 0.004 | 1 | ||
| 81:01|04:01 | 0.004 | 1 | ||
| 42:01|04:01 | 0.003 | 1 | ||
| 57:01:01|04:01 | 0.006 | 2 | ||
| 58:01|04:01 | 0.003 | 1 | ||
| Cases (n = 93) | Controls (n = 89) | |||
| DRB1|DQB1 Haplotype | ||||
| 01:02:01|05:01:01 | 0.038 | 7 | 0.073 | 13 |
| 12:01|05:01:01 | 0.038 | 7 | 0.062 | 11 |
| 13:01:01|05:01:01 | 0.032 | 6 | 0.028 | 5 |
| 01:01:01|05:01:01 | 0.011 | 2 | 0.006 | 1 |
| 10:01|05:01:01 | 0.011 | 2 | 0.011 | 2 |
| 13:02:01|05:01:01 | 0.005 | 1 | ||
| 14:01|05:01:01 | 0.006 | 1 | ||
| 15:03|05:01:01 | 0.006 | 1 | ||
Only B|C haplotypes containing the C*04:01 and DRB1\DQB1 haplotypes containing DQB1*05:01:01 are listed. Frequency data for class I and class II haplotypes are listed in Supplementary Table 2.