. Author manuscript; available in PMC: 2013 Dec 1.

Published in final edited form as: J Clin Pharmacol. 2011 Dec 15;52(12):10.1177/0091270011424153. doi: 10.1177/0091270011424153

Table III.

Univariate and Multivariate Analysis of Predictors of the Change in HDL and LDL Cholesterol After 3 Months of Aromatase Inhibitor Therapy in the Overall Lipid Analysis Cohort (n = 246)

Change Correlates
HDL Cholesterol	LDL Cholesterol
Baseline total cholesterol (r² = −0.023, P = .017)	Baseline total cholesterol (r² = −0.178, P <.001)
Baseline HDL cholesterol^a (r² = −0.125, P < .001)	Baseline LDL cholesterol^a (r² = −0.252, P < .001)
Baseline LDL/HDL ratio (r² = 0.054, P < .001)	Baseline LDL/HDL ratio (r² = −0.088, P < .001)
	Prior tamoxifen use^a (r² = 0.123, P < .001)

HDL, high-density lipoprotein; LDL, low-density lipoprotein.

Independent predictors upon stepwise regression analysis.