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. Author manuscript; available in PMC: 2013 Apr 4.
Published in final edited form as: Cell. 2009 Sep 4;138(5):855–869. doi: 10.1016/j.cell.2009.07.042

Figure 3. IdicYp and isoYp chromosomes confirmed by metaphase FISH.

Figure 3

(A) Probe hybridization sites shown below chrY schematic. At right: Hybridization to chrY of normal male control produced expected pattern of red and green signals. Chromosome counterstained with DAPI (blue).

(B) Hybridizations to presumed idicYp chromosomes with breakpoints in Yq palindromes P8, P6, P5, P4, P3 and P1, or in IR2 inverted repeat. Hybridization sites shown below schematic of each predicted idicYp; targeted palindrome or inverted repeat lies at center of each schematic. At right: FISH produced predicted red-green-green-red patterns.

(C) Hybridization to presumed isoYp or idicYp chromosomes with breakpoints in heterochromatin.

All FISH micrographs at same magnification.