Figure 7. Model of DSB resolution in MSY direct and inverted repeats (palindromes) by NCO and CO pathways.
Sequence identity between palindrome arms or inverted repeats, and between direct repeats, is maintained by NCO resolution of DSBs; such gene conversion could occur between sister chromatids or within a single chromatid. In the case of palindromes or inverted repeats, CO resolution between sister chromatids can generate an idicY and an acentric fragment, while CO resolution within a chromatid results in inversion. In the case of direct repeats, CO resolution between sister chromatids can generate a duplication and an interstitial deletion, while CO resolution within a chromatid yields an interstitial deletion and an acentric fragment.
