Table 1.
TN patients (n = 2806) | TF patients (n = 1856) | P-valuea | TF patients |
P-valueb | |||
---|---|---|---|---|---|---|---|
<3 months (n = 313) | 3–12 months (n = 299) | >12 months (n = 1244) | |||||
Age (years, mean ± SD) | 51.1 | 48.3 | 0.0032 | 47.4 | 49.9 | 48.1 | 0.22 |
Male (%) | 61.6 | 61 | 0.66 | 64.2 | 59.2 | 60.7 | 0.58 |
Black (%) | 15.1 | 10.6 | 0.04 | 15.3 | 9.7 | 9.6 | 0.90 |
Weight (kg) | 73.5 | 66.5 | <0.0001 | 71.2 | 68.3 | 65.0 | <0.0001 |
BMI (kg/m2, mean ± SD) | 25.4 | 23.5 | <0.0001 | 24.2 | 23.7 | 23.3 | 0.0030 |
Vintage (years, mean ± SD)c | 3.6 | 4.2 | <0.0001 | – | – | – | – |
Comorbidities (%) | |||||||
Coronary artery disease | 39.5 | 33.1 | 0.69 | 27.9 | 36.2 | 33.7 | 0.55 |
Congestive heart failure | 21.5 | 28.6 | <0.0001 | 28.9 | 32.9 | 27.5 | 0.64 |
Other cardiac disease | 21.9 | 33.1 | <0.0001 | 26.6 | 35.7 | 34.0 | 0.11 |
Diabetes | 26.9 | 17.5 | <0.0001 | 26.0 | 24.2 | 13.7 | <0.0001 |
Hypertension | 80.6 | 79.5 | 0.51 | 83.2 | 84.8 | 77.4 | 0.03 |
Cerebrovascular disease | 7.8 | 8.4 | 0.71 | 9.4 | 9.5 | 8.0 | 0.51 |
Peripheral vascular disease | 15.0 | 15.8 | 0.06 | 15.9 | 15.9 | 15.7 | 0.95 |
Cancer | 6.0 | 7.7 | 0.0035 | 5.5 | 7.1 | 8.4 | 0.19 |
Lung disease | 6.2 | 6.7 | 0.35 | 5.2 | 6.7 | 7.1 | 0.17 |
Gastrointestinal bleed | 3.9 | 4.7 | 0.08 | 6.2 | 6.1 | 4.0 | 0.07 |
Neurological disease | 7.4 | 8.9 | 0.004 | 5.8 | 8.1 | 9.8 | 0.02 |
Psychiatric disorder | 14.9 | 21.5 | <0.0001 | 22.4 | 22.6 | 21.1 | 0.61 |
Recurrent cellulitis/gangrene | 4.1 | 7.0 | 0.0002 | 7.8 | 5.1 | 7.3 | 0.44 |
Vascular access (%) | |||||||
Arteriovenous fistula | 70.1 | 63.9 | 0.06 | 52.0 | 60.9 | 67.7 | 0.0030 |
Graft | 15.2 | 18.5 | 0.01 | 14.8 | 15.8 | 20.1 | <0.0001 |
Catheter | 14.7 | 17.6 | 0.0003 | 33.2 | 23.2 | 12.2 | <0.0001 |
Laboratory values (mean ± SD) | |||||||
Hemoglobin (g/dL) | 11.6 | 11.1 | <0.0001 | 9.8 | 11.2 | 11.3 | <0.0001 |
Albumin (g/dL) | 3.9 | 3.7 | <0.0001 | 3.4 | 3.7 | 3.8 | <0.0001 |
Calcium (mg/dL) | 9.4 | 9.5 | 0.35 | 9.3 | 9.4 | 9.6 | 0.0001 |
Phosphorus (mg/dL) | 5.8 | 5.8 | 0.25 | 5.7 | 5.9 | 5.7 | 0.33 |
PTH (pg/mL) | 325 | 371 | 0.03 | 478 | 333 | 360 | 0.04 |
Ferritin (ng/mL) | 423 | 426 | 0.01 | 325 | 428 | 445 | 0.01 |
Model adjusted for country and study phase and accounted for facility clustering.
aTest for difference between TF and TN patients in adjusted models.
bTest for trend across TF patient subgroups in adjusted models.
cTime since first ever dialysis from TN patients, and time since TF for TF patients.
BMI, body mass index; SD, standard deviation; PTH, parathyroid hormone.