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. 2012 Sep 30;27(12):4464–4472. doi: 10.1093/ndt/gfs386

Table 1.

Patient characteristics at study enrollment

  TN patients (n = 2806) TF patients (n = 1856) P-valuea TF patients
P-valueb
<3 months (n = 313) 3–12 months (n = 299) >12 months (n = 1244)
Age (years, mean ± SD) 51.1 48.3 0.0032 47.4 49.9 48.1 0.22
Male (%) 61.6 61 0.66 64.2 59.2 60.7 0.58
Black (%) 15.1 10.6 0.04 15.3 9.7 9.6 0.90
Weight (kg) 73.5 66.5 <0.0001 71.2 68.3 65.0 <0.0001
BMI (kg/m2, mean ± SD) 25.4 23.5 <0.0001 24.2 23.7 23.3 0.0030
Vintage (years, mean ± SD)c 3.6 4.2 <0.0001
Comorbidities (%)
 Coronary artery disease 39.5 33.1 0.69 27.9 36.2 33.7 0.55
 Congestive heart failure 21.5 28.6 <0.0001 28.9 32.9 27.5 0.64
 Other cardiac disease 21.9 33.1 <0.0001 26.6 35.7 34.0 0.11
 Diabetes 26.9 17.5 <0.0001 26.0 24.2 13.7 <0.0001
 Hypertension 80.6 79.5 0.51 83.2 84.8 77.4 0.03
 Cerebrovascular disease 7.8 8.4 0.71 9.4 9.5 8.0 0.51
 Peripheral vascular disease 15.0 15.8 0.06 15.9 15.9 15.7 0.95
 Cancer 6.0 7.7 0.0035 5.5 7.1 8.4 0.19
 Lung disease 6.2 6.7 0.35 5.2 6.7 7.1 0.17
 Gastrointestinal bleed 3.9 4.7 0.08 6.2 6.1 4.0 0.07
 Neurological disease 7.4 8.9 0.004 5.8 8.1 9.8 0.02
 Psychiatric disorder 14.9 21.5 <0.0001 22.4 22.6 21.1 0.61
 Recurrent cellulitis/gangrene 4.1 7.0 0.0002 7.8 5.1 7.3 0.44
Vascular access (%)
 Arteriovenous fistula 70.1 63.9 0.06 52.0 60.9 67.7 0.0030
 Graft 15.2 18.5 0.01 14.8 15.8 20.1 <0.0001
 Catheter 14.7 17.6 0.0003 33.2 23.2 12.2 <0.0001
Laboratory values (mean ± SD)
 Hemoglobin (g/dL) 11.6 11.1 <0.0001 9.8 11.2 11.3 <0.0001
 Albumin (g/dL) 3.9 3.7 <0.0001 3.4 3.7 3.8 <0.0001
 Calcium (mg/dL) 9.4 9.5 0.35 9.3 9.4 9.6 0.0001
 Phosphorus (mg/dL) 5.8 5.8 0.25 5.7 5.9 5.7 0.33
 PTH (pg/mL) 325 371 0.03 478 333 360 0.04
 Ferritin (ng/mL) 423 426 0.01 325 428 445 0.01

Model adjusted for country and study phase and accounted for facility clustering.

aTest for difference between TF and TN patients in adjusted models.

bTest for trend across TF patient subgroups in adjusted models.

cTime since first ever dialysis from TN patients, and time since TF for TF patients.

BMI, body mass index; SD, standard deviation; PTH, parathyroid hormone.