Table 3.
Characteristics of 12 children with virologic treatment failure after 12 months of antiretroviral therapy
| Serial number | Age at ART initiation(months) | WHO clinical stage | ART regimen | Other significant OIs/social issues | Outcome |
|---|---|---|---|---|---|
| 1 |
4 |
2 |
ZDV-3TC-NVP |
None |
Lost to follow-up |
| 2 |
4 |
3 |
D4T-3TC-LPV/r |
None |
Switched to second line ART |
| 3 |
5 |
3 |
ZDV-3TC-NVP |
3 Pneumonia episodes |
Switched to second line ART |
| 4 |
7 |
3 |
D4T-3TC-ABC |
Tuberculosis |
Died |
| 5 |
11 |
3 |
ZDV-3TC-ABC |
Tuberculosis |
Lost to follow-up |
| 6 |
6 |
3 |
D4T-3TC-NVP |
Chronic suppurative otitis media |
Switched to second line ART |
| 7 |
6 |
3 |
D4T-3TC-NVP |
None |
Lost to follow-up |
| 8 |
4 |
2 |
ZDV-3TC-NVP |
None |
Switched to second line ART |
| 9 |
10 |
3 |
D4T-3TC-NVP |
Poor adherence to ART |
Switched to second line ART |
| 10 |
10 |
2 |
D4T-3TC-LPV/r |
Teenage Mother |
Lost to follow-up |
| 11 |
8 |
3 |
D4T-3TC-NVP |
None |
Switched to second line ART |
| 12 | 10 | 4 | ZDV-3TC-NVP | Anemia probably due to ZDV | Died |
WHO= World Health Organization; ART= Antiretroviral therapy; OI= opportunistic infections.