Table 1.
Skin color, tanning and freckling genetic scores.
skin color score | |||||
---|---|---|---|---|---|
gene | SNP | chromosome | chromosomal location |
major/minor alleles |
risk allelea |
IRF4 | rs12203592 | 6p25.3 | 341321 | C/T | T |
TYR | rs1042602 | 11q14.3 | 88551344 | C/A | A |
HERC2 | rs12913832 | 15q13.1 | 26039213 | G/A | G |
MC1R | rs1805007 | 16q24.3 | 88513618 | C/T | T |
ASIP | rs4911414 | 20q11.22 | 32193105 | G/T | T |
ASIP | rs1015362 | 20q11.22 | 32202273 | G/A | G |
tanning score | |||||
gene | SNP | chromosome |
chromosomal
location |
major/minor
alleles |
risk
allele b |
PPARGC1B | rs32579 | 5q32 | 149191041 | G/A | G |
IRF4 | rs12203592 | 6p25.3 | 341321 | C/T | T |
IRF4/EXOC2 | rs12210050 | 6p25.3 | 420489 | C/T | T |
TYR | rs1393350 | 11q14.3 | 88650694 | G/A | A |
CALCOCO1/HOXC13 | rs7969151 | 12q13.13 | 52445544 | G/A | A |
PAPOLA/VRK1 | rs17094273 | 14q32.2 | 96173560 | G/A | A |
HERC2 | rs12913832 | 15q13.1 | 26039213 | G/A | G |
CPNE7/DPEP1 | rs154659 | 16q24.3 | 88194838 | T/C | C |
MC1R | rs1805007 | 16q24.3 | 88513618 | C/T | T |
DBNDD1 | rs11648785 | 16q24.3 | 88612062 | C/T | C |
ASIP | rs4911414 | 20q11.22 | 32193105 | G/T | T |
ASIP | rs1015362 | 20q11.22 | 32202273 | G/A | G |
PRDM15 | rs7279297 | 21q22.3 | 42100984 | A/G | A |
freckling score | |||||
gene | SNP | chromosome |
chromosomal
location |
major/minor
alleles |
risk
allele c |
IRF4 | rs12203592 | 6p25.3 | 341321 | C/T | T |
BNC2 | rs2153271 | 9p22.2 | 16854521 | A/G | A |
TYR | rs1042602 | 11q14.3 | 88551344 | C/A | C |
TYR | rs1393350 | 11q14.3 | 88650694 | G/A | A |
MC1R | rs1805007 | 16q24.3 | 88513618 | C/T | T |
ASIP | rs4911414 | 20q11.22 | 32193105 | G/T | T |
ASIP | rs1015362 | 20q11.22 | 32202273 | G/A | G |
EIF6 | rs619865 | 20q11.22 | 33331111 | G/A | A |
The risk allele is the allele associated with lighter skin pigmentation.
The risk allele is the allele associated with higher propensity to burn.
The risk allele is the allele associated with a greater likelihood of having freckles.