Table 1.
General clinical and renal histopathological profiles of patients with lupus nephritis at renal biopsy
| Number of patients | 218 | C3 (mean ± SD) (g/l) | 0.45 ± 0.23 |
|---|---|---|---|
| Gender (male/female) |
33/185 |
Anti-nuclear antibody (ANA) (+) No.(%) |
215 (98.6) |
| Age (mean ± SD) (years) |
32.5 ± 11.3 |
Anti-double stranded DNA antibody (ds-DNA) (+) No.(%) |
153 (70.6) |
| Follow-up time (median, range) (months) |
41 (1,360) |
Anti-SSA antibody (+) No.(%) |
102 (46.8) |
| Fever (non-infectious) No.(%) |
69 31.7) |
Anti-SSB antibody (+) No.(%) |
25 (11.5) |
| Malar rash No.(%) |
118 (54.1) |
Anti-Smith antibody(Sm) (+) No.(%) |
53 (24.3) |
| Photosensitivity No.(%) |
47 (21.6) |
Anti-ribonucleoprotein (RNP) antibody (+) No.(%) |
66 (30.3) |
| Oral ulcer No.(%) |
64 (29.4) |
Anti- cardiolipin antibody (+) No.(%) |
16 (7.3) |
| Alopecia No.(%) |
68 (31.2) |
SLEDAI (mean ± s.d.) |
17.6 ± 5.8 |
| Arthralgia No.(%) |
115 (52.8) |
Activity indices (AI) score (median, range) |
8 (0,19) |
| Serositis No.(%) |
34 (15.6) |
Endocapillary hypercellualrity (median, range) |
3 (0,-3) |
| Neurologic disorder No.(%) |
14 (6.4) |
Cellular crescents (median, range) |
0 (0,6) |
| Anemia No.(%) |
147 (67.4) |
Karyorrhexis/fibrinoid necrosis (median, range) |
0 (0,6) |
| Leukocytopenia No.(%) |
102 (46.8) |
Subendothelial hyaline deposits (median, range) |
1 (0,3) |
| Thrombocytopenia No.(%) |
64 (29.4) |
Interstitial inflammatory cell infiltration (median, range) |
1 (0,3) |
| Hematuria No.(%) |
168 (77.1) |
Glomerular leukocyte infiltration (median, range) |
1 (0,12) |
| Leukocyturia (non-infection) No.(%) |
118 (54.1) |
Chronicity indices (CI) score (median, range) |
2 (0,10) |
| Acute renal failure No.(%) |
39 (17.9) |
Glomerular sclerosis (median, range) |
0 (0,3) |
| Hemoglobin (mean ± SD) (g/l) |
100.92 ± 26.36 |
Fibrous crescents (median, range) |
0 (0,3) |
| Urine protein (median, range) (g/24 hours) |
4.36 (0–17) |
Tubular atrophy (median, range) |
1 (0,3) |
| Serum creatinine (median, range) (μmol/l) | 82.0 (37,1000) | Interstitial fibrosis (median, range) | 1 (0,3) |
SSA/SSB, Sjögren’s syndrome A/Bantigen; SSB, Sjögren’s syndrome B antigen; SLEDAI, SLE Disease Activity Index.