Table 3.
Associations between presence of anti-C1q autoantibodies, levels of C1q and histopathological parameters of patients with lupus nephritis
|
Patients with anti-C1q autoantibodies |
Patients without anti-C1q autoantibodies |
r value(P value) |
Patients with levels of C1q above 40.97 μg/ml |
Patients with levels of C1q under 40.97 μg/ml |
r value(P value) | |
|---|---|---|---|---|---|---|
| Median(range) | Median(range) | Median(range) | Median(range) | |||
|
Histopathological data | ||||||
| Activity Indices score |
9(0,19) |
7(0,16) |
0.238(<0.001) |
4(0,19) |
9(0,19) |
−0.327(<0.001) |
| Endocapillary hypercellularity |
3(0,3) |
2(0,3) |
0.249(<0.001) |
3(0,3) |
1(0,3) |
−0.337(<0.001) |
| Cellular crescents |
2(0,6) |
0(0,6) |
0.167(0.013) |
2(0,6) |
0(0,6) |
−0.182(0.007) |
| Karyorrhexis/fibrinoid necrosis |
2(0,6) |
0(0,4) |
0.175(0.009) |
2(0,6) |
0(0,2) |
−0.310(<0.001) |
| Subendothelial hyaline deposits |
1(0,3) |
1(0,3) |
0.171(0.012) |
1(0,3) |
0(0,3) |
−0.312(<0.001) |
| Interstitial inflammation |
1(0,3) |
1(0,3) |
NS |
1(0,3) |
1(0,3) |
NS |
| Leukocyte infiltration |
1(0,3) |
1(0,3) |
0.159(0.019) |
1(0,3) |
1(0,3) |
−0.246(<0.001) |
| Chronicity Indices score |
2(0,9) |
2(0,10) |
NS |
2(0,10) |
2(0,9) |
NS |
| Glomerular sclerosis |
0(0,3) |
0(0,3) |
NS |
0(0,3) |
0(0,3) |
0.146(0.031) |
| Fibrous crescents |
0(0,3) |
0(0,3) |
NS |
0(0,3) |
0(0,2) |
NS |
| Tubular atrophy |
1(0,3) |
1(0,3) |
NS |
1(0,3) |
1(0,3) |
NS |
| Interstitial fibrosis | 1(0,3) | 1(0,3) | NS | 1(0,3) | 1(0,3) | NS |
NS, no significance.