Table 2.

Inhibition of β-haematin formation

Compound	Concentration	Inhibitionb	IC50 c	CQ
	(mM)	(%)	(mM)	indexa
Chloroquine	0.5 – 20	83 ± 1.07	3 ± 0.16	-
1e	0.5 – 19	25 ± 2.62	> 19	> 6.33
1f	0.5 – 20	14 ± 0.43	> 20	> 6.66
2e	0.5 – 19	26 ± 3.57	> 19	> 6.33

^a calculated as compound IC₅₀/CQ IC₅₀.

^b results are expressed as mean ± standard deviation at the highest tested concentration.

^c results are expressed as mean ± standard error.