Table 1.
The eQTL hotspots and their candidate regulators from GFlasso and other previous analyses
| eQTL Hotspot | eQTL module size | cis genes in eQTL module GFlasso | Yvert et al. [[17]] | Zhu et al. [[9]] | Lee et al. [[8]] |
|---|---|---|---|---|---|
|
*II:380000 |
106 |
NRG1 TIP1 TAT1 TEC1 ECM33 |
none |
none |
RDH54 SEC18 SPT7 |
|
*II:560000 |
722 |
AMN1 MAK5 CNS1 TBs1 TOS1 ARA1 SUP45 CSH1 RPB5 SDS24 ENP1 REI1 |
AMN1 MAK5 |
AMN1 CNS1 TBS1 TOS1 ARA1 SUP45 CSH1 |
AMN1 CNS1 TOS2 ABD1 PRP5 TRS20 |
|
*III:100000 |
225 |
LEU2 ILV6 NFS1 CIT2 PGS1 RER1 HIS4 FRM2 KCC4 |
LEU2 |
LEU2 ILV6 NFS1 CIT2 MATALPHA1 |
LEU2 ILV6 PGS1 |
|
*III:200000 |
62 |
MATALPHA1 MATALPHA2 PHO87 BUD5 TAF2 |
MATALPHA1 |
MATALPHA1 |
MATALPHA1 MATALPHA2 TBK1 |
|
IV:1500000 |
46 |
YRF1-1 YDR539W YDR541C |
- |
- |
- |
|
*V:110000 |
45 |
URA3 NPP2 |
URA3 |
URA3 |
URA3 NPP2 PAC2 |
|
V:350000 |
618 |
RPS24A RPS8B RTT105 |
- |
- |
- |
|
V:420000 |
405 |
LCP5 NSA2 |
- |
- |
- |
|
V:460000 |
42 |
YER138C UBP5 RTR1 |
- |
- |
- |
|
VII:50000 |
350 |
RAI1 TAD1 KAP114 |
- |
- |
- |
|
*VIII:110000 |
147 |
GPA1 YAP3 ERG11 LAG1 SHO1 ETP1 YLF2 LEU5 |
GPA1 |
GPA1 |
GPA1 STP2 NEM1 |
|
X:20000 |
48 |
YJL225C VTH2 FSP2 REE1 |
- |
- |
- |
|
XII:610000 |
53 |
TOP3 |
- |
- |
- |
|
*XII:680000 |
185 |
HAP1 NEJ1 SSP120 |
HAP1 |
HAP1 |
HAP1 NEJ1 GSY2 |
|
XII:780000 |
44 |
REC102 PEX30 FKS1 GAS2 |
- |
- |
- |
|
*XII:1070000 |
54 |
YRF1-4 YRF1-5 YLR464W YLR462W |
SIR3 |
YRF1-4 YRF1-5 YLR464W |
SIR3 HMG2 ECM7 |
|
*XII:70000 |
76 |
MDM1 |
none |
none |
ARG81 TAF13 CAC2 |
|
*XIV:490000 |
448 |
SAL1 TOP2 MKT1 THO2 MSK1 TPM1 LAT1 SWS2 |
none |
SAL1 TOP2 |
TOP2 MKT1 MSK1 |
|
XIV:550000 |
45 |
COG6 YIP3 HDA1 |
- |
- |
- |
|
XV:90000 |
85 |
ZEO1 RFC4 HM11 INO4 NDJ1 SKM1 HAL9 |
- |
- |
- |
|
*XV:180000 |
406 |
PHM7 ATG19 WRS1 RFC4 |
none |
PHM7 |
PHM7 ATG19 BRX1 |
| *XV:59000 | 120 | LSC1 YOR131C RAS1 INP53 OST2 PIN2 | CAT5 | none | CAT5 ADE2 ORT1 |
* denotes a previously discovered hotspot.