Table 4.
MDR1 C3435T and G2677T allele and genotype frequencies in CD, UC and control group
| Controls (n = 120) | CD (n = 199) | p value | UC (n = 109) | p value | |
|---|---|---|---|---|---|
|
C3435T |
|
|
|
|
|
| Allele frequencies (%) |
|
|
|
|
|
| Allele C |
132 (55.5) |
208 (52.5) |
0.47 |
100 (46.3) |
0.051 |
| Allele T |
106 (44.5) |
188 (47.5) |
116 (53.7) |
||
| Genotype frequencies (%) |
|
|
|
|
|
| CC |
32 (26.9) |
61 (30.8) |
0.52 |
23 (21.3) |
0.35 |
| CT |
68 (57.1) |
86 (43.4) |
0.02 |
54 (50.0) |
0.29 |
| TT |
19 (16.0) |
51 (25.8) |
0.05 |
31 (28.7) |
0.02 |
|
G2677T/A |
|
|
|
|
|
| Allele frequencies (%) |
|
|
|
|
|
| Allele G |
149 (64.2) |
239 (61.6) |
0.51 |
119 (55.1) |
0.05 |
| Allele T |
83 (35.8) |
149 (38.4) |
97 (44.9) |
||
| Genotype frequencies (%) |
|
|
|
|
|
| GG |
47 (40.5) |
82 (42.3) |
0.72 |
33 (30.5) |
0.16 |
| GT |
55 (47.4) |
75 (38.6) |
0.16 |
53 (49.1) |
0.69 |
| TT | 14 (12.1) | 37 (19.1) | 0.11 | 22 (20.4) | 0.10 |