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. 2013 Apr 4;9(4):e1003401. doi: 10.1371/journal.pgen.1003401

Figure 4. BPA exposure altered total mRNA expression of imprinted genes relative to reference genes.

Figure 4

Samples from control, lower dose and upper dose exposure groups were analyzed for total expression of the imprinted (A) Snrpn, (B) Igf2, (C) Kcnq1ot1, (D) Cdkn1c and (E and F) Ube3a genes with sample sizes (n) indicated. Assayed samples included embryos (Igf2), placentas (Snrpn, Kcnq1ot1, Cdkn1c, and Ube3a) or brains (Ube3a) showing normal, monoallelic (black circle) or biallelic expression (red circle). Average total expression in each exposure group is indicated with a black horizontal line; a = P<0.05; b = P<0.01 and c = P<0.001.