Figure 5. Mlx is functionally important in the fat body.

(A) mRNA expression of mondo and mlx in dissected tissues of 3^rd instar larvae measured by quantitative RT-PCR. rp49 was used as a reference gene. (B) Tissue specific rescue of pupation and adult emergence of the mlx¹ mutants using neuronal (Elav), muscle (Mef2), or fat body (ppl and r⁴) –specific GAL4 drivers. (C) Fat body –specific (r⁴-GAL4) expression of transgenic mlx rescues the elevated circulating glucose in mlx¹ mutants. Error bars represent ± SEM (** p<0.01).