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Representative images of immunohistochemical staining for CD68+ (macrophages) and CD3+ (T lymphocytes) cells in cardiac tissue (400× magnification). Bars represent quantification of infiltrating CD68+ and CD3+ cells (cells/mm2). TP, L, low-dose triptolide (100 μg/kg/day); TP, M, medium-dose triptolide (200 μg/kg/day); TP, H, high-dose triptolide (400 μg/kg/day). *P < 0.05 versus control; #P < 0.05 versus DM, n = 10 per group.
