Table 2.
Echocardiographic assessment of In Vivo residual LV function at 4 weeks post-MI
| Parameter | CV | DM | Sham MI | MI | DM + MI |
|---|---|---|---|---|---|
| LVFS,% |
43.4 ± 1.9 |
34.3 ± 1.1* |
40.4 ± 1.0 |
25.2 ± 2.2†# |
17.9 ± 0.7*†#‡ |
| LVEF,% |
73.3 ± 2.3 |
61.5 ± 1.5* |
69.5 ± 1.2 |
47.5 ± 3.5†# |
35.5 ± 1.4*†#‡ |
| LVIDd, mm |
6.3 ± 0.22 |
7.7 ± 0.20* |
6.6 ± 0.24 |
9.3 ± 0.55†# |
9.2 ± 0.67*† |
| LVIDs, mm |
3.6 ± 0.23 |
5.1 ± 0.17* |
4.2 ± 0.19 |
7.0 ± 0.55†# |
7.8 ± 0.37*†# |
| Heart Rate, bpm | 350 ± 23.5 | 241 ± 9.0* | 376 ± 16.5 | 361 ± 11.1# | 299 ± 9.3†#‡ |
LVFS, left ventricular fractional shortening; LVEF, left ventricular ejection fraction; LVIDd, left ventricular internal dimension, diastolic; LVIDs, left ventricular internal dimension, systolic. Values are mean ± standard error of the mean of four to six animals. *P < 0.05 vs. CV; †P < 0.05 vs. Sham MI; #P < 0.05 vs. DM; ‡P < 0.05 vs. MI.