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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Nitric Oxide. 2013 Jan 28;30:17–25. doi: 10.1016/j.niox.2013.01.003

Figure 3.

Figure 3

JS-K induces cGMP formation in U87 cells which can be inhibited by ODQ. Cells were exposed to increasing concentrations of JS-K (1 μM, 5 μM, 10 μM and 15 μM) with and without pretreatment with ODQ. Cells exposed to DMSO (max. concentration of 0.3%) were used as solvent control. The maximum of intracellular cGMP release can be detected 60 min (black) and 90 min (grey) after JS-K exposure. **p 0.01, ***p 0.001 t-test compared to control (Ctr).