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Effect of JS-K on day 12 and day 19 after tumor inoculation: a) tumor volume, b) edema volume, and c) normalized iAUC60 (normalized to contralateral brain) in control (Ctr, grey diamonds) and JS-K-treated (white triangles) rats. There was no significant difference between the two groups on either time point. Tumor volumes increased with time, whereas iAUC60 decreased. Mild peritumoral edema was detected in some animals on day 19.
