Table 1. The anti-worm and anti-egg effects in vaccinated-mice.
Group | worm burden (mean±SEM) | number of eggs/g liver (mean±SEM) | Percent reduction in worm burden | Percent reduction in egg production |
pVAX1 | 36.75±3.48 | 37851.60±1943.62 | / | / |
pVAX1-Sj26GST | 26.08±1.99 | 28282.70±2139.17 | 29.04 | 25.28 |
pVAX1-Sj26GST+CpG | 25.06±1.85 | 26589.54±1826.65 | 31.82 | 29.75 |
pVAX1-Sj26GST+R848 | 24.5±1.24 | 27697.58±1411.21 | 33.33 | 26.83 |
pVAX1-Sj26GST+CpG+R848 | 17.02±0.80 | 19058.03±1377.80 | 53.69 | 49.65 |
CpG | 36.4±1.95 | 37576.69±1280.64 | 9.52 | 7.26 |
R848 | 35.2±2.03 | 36760.76±2323.49 | 4.22 | 2.88 |
The mean worm/liver egg burdens were calculated using results from sixteen mice from two independent experiments (n = 8). Percent protection in the two independent experiments was calculated by comparing their results with the results obtained from the pVAX1 group. Results are expressed as means± standard error of the mean.