Table 3.
Comparison of the proposed method, EDGE and Sohn’s method for the single group test by FPR (proportion of falsely rejected hypotheses over the total number of rejected hypotheses) and sensitivity (proportion of true positives correctly identified)
| Proposeda | Proposedb | EDGE | Sohn’s | |||
|---|---|---|---|---|---|---|
|
Π0=0.05 |
FDR = 0.01 |
FPR |
0.0016 |
0.0127 |
0.0100 |
0.0091 |
| |
|
Sensitivity |
0.7606 |
0.6864 |
0.4742 |
0.5160 |
| |
FDR = 0.05 |
FPR |
0.0180 |
0.0541 |
0.0459 |
0.0514 |
| |
|
Sensitivity |
0.8440 |
0.7858 |
0.6378 |
0.6616 |
|
Π0=0.2 |
FDR = 0.01 |
FPR |
0.0003 |
0.0084 |
0.0079 |
0.0078 |
| |
|
Sensitivity |
0.7716 |
0.7851 |
0.6210 |
0.6302 |
| |
FDR = 0.05 |
FPR |
0.0070 |
0.0409 |
0.0363 |
0.0408 |
| |
|
Sensitivity |
0.8644 |
0.8667 |
0.7652 |
0.7641 |
|
Π0=0.5 |
FDR = 0.01 |
FPR |
0.0002 |
0.0053 |
0.0041 |
0.0051 |
| |
|
Sensitivity |
0.7731 |
0.8329 |
0.7021 |
0.7031 |
| |
FDR = 0.05 |
FPR |
0.0025 |
0.0251 |
0.0238 |
0.0244 |
| Sensitivity | 0.8709 | 0.9049 | 0.8285 | 0.8261 |
Proposed b uses (7) for computing p-values and Proposed a, EDGE and Sohn’s use (8).