Table 1. Overview of diseases in the study.
Disease Name | GEO Accession | Number of DEGs | Number of Drug Targets |
Malaria | GSE5418 | 1658 | 220 |
Acute myeloid leukemia | GSE30029 | 5325 | 159 |
AIDS | GSE16363 | 1839 | 40 |
Idiopathic pulmonary fibrosis | GSE24206 | 14 | 31 |
Thyroid carcinoma | GSE29265 | 3979 | 37 |
Colorectal cancer | GSE35602 | 2952 | 304 |
Crohn's disease | GSE10714 | 12 | 75 |
Diabetes type 1 | GSE11907 | 471 | 68 |
Hepatitis C | GSE11907 | 2626 | 229 |
Hepatocellular carcinoma | GSE36411 | 2425 | 210 |
HIV | GSE18233 | 463 | 159 |
Hyperplastic polyposis syndrome | GSE19963 | 897 | 3 |
Ischemic cardiomyopathy | GSE5406 | 146 | 5 |
Ischemic stroke | GSE16561 | 290 | 322 |
Liver cirrhosis | GSE36411 | 121 | 10 |
Melanoma | GSE15605 | 4038 | 175 |
Melanoma with metastasis | GSE15605 | 5469 | 73 |
Multiple sclerosis | GSE32988 | 428 | 379 |
Obesity | GSE12050 | 1631 | 245 |
Ovarian cancer | GSE38666 | 3862 | 15 |
Parkinson's disease | GSE22491 | 1142 | 347 |
Periodontitis | GSE10334 | 1416 | 28 |
Psoriasis | GSE26866 | 310 | 351 |
Sarcoidosis | GSE34608 | 5803 | 13 |
Scleroderma | GSE33463 | 232 | 11 |
Septic shock | GSE26440 | 3455 | 131 |
Sickle-cell disease | GSE16728 | 559 | 4 |
Sjogren's syndrome | GSE23117 | 271 | 8 |
Systemic Lupus Erythematosus | GSE11907 | 476 | 62 |
Ulcerative colitis | GSE10714 | 871 | 57 |
For each disease, the table lists the GEO accession for the gene expression data sets, the number of differentially expressed genes (DEGs), and the number of drug targets associated to the disease in Integrity. The number of DEGs and drug targets are based on Entrez Gene identifiers.