Figure 5. Lung inflammatory dendritic cells (iDCs) show reduced FITC-OVA uptake and maturation in β5i KO mice.

The percentages of FITC−OVA+ of iDCs and MHC II+ of FITC-OVA iDCs were measured by flow cytometry from the homogenized lungs 24 h post intranasally FITC-OVA application in mice that have been sensitized with OVA/Alum. Data are representative of two independent experiments and shown as the mean ± SEM (n = 10). (*) and (+) represent comparison of PBS vs OVA and Wt OVA vs KO OVA treatment groups respectively. **^/++P<0.01, ***^/+++P<0.001.