Figure 6. Reduced pulmonary Th2 response is not due to intrinsic defects of iDCs in β5i KO mice.

(A) OVA/Alum asthma induction protocol. (B) Differential cell count of BAL cytospins. (C) Lung Th2 and Treg cell profile. Wt bone marrow derived dendritic cells (BMDCs) were injected i.p. with 0.8×10⁶/mouse per injection. The percentages of IL5+ IL13+ and CD25+ FoxP3+ of CD4+ cells were measured by flow cytometry from the homogenized lungs. The data are representative of two independent experiments and shown as the mean ± SEM (n = 6). (*) and (+) represent comparison of PBS vs OVA and Wt OVA vs KO OVA treatment groups respectively. *^/+P<0.05, **^/++P<0.01, ***^/+++P<0.001.