Table 2. Neuropsychological test results for acromegaly groups and healthy controls.
| Cured patients | Naïve patients | Healthy subjects | |
| Attention | |||
| Simple attention test, RT (sec.) | 0.488 (0.06) | 0.467 (0.06) | 0.449 (0.06) |
| Conditional attention test, RT (sec.) | 0.387 (0.13) | 0.399 (0.05) | 0.403 (0.08) |
| Trail Making Test A, time (sec.) | 56 (30.04) | 61.1 (27.92) | 39.5 (9.26) |
| Executive functioning | |||
| Trail Making Test B, time (sec.) | 135 (77.24) | 186.4 (93.48) | 89.6 (25.71) |
| Stroop Color-Word Test, RT (sec.) | 1.62 (0.39) | 1.64 (0.59) | 1.44 (0.31) |
| Tower of Hanoi test, total time (sec.) | 177 (144.32) | 246 (177.70) | 154 (112.19) |
| Memory | |||
| Digit Span Test (forward) | 7.60 (1.95) | 6.94 (1.60) | 8.17 (1.11) |
| Digit Span Test (backward) | 5.33 (1.50) | 4.13 (1.53)a,d | 6.17 (1.26) |
| LMW-R | |||
| True Recall Index | 8.29 (1.01)a,e | 8.36 (0.83) | 8.98 (0.50) |
| Confabulation Index | 4.56 (3.43) | 5.93 (3.44)b,e | 2.43 (1.57) |
| Delayed recall | 6.94 (1.09)c,f | 7.40 (1.45)c,f | 9.25 (0.90) |
| Complex Figure Test | |||
| Copy condition | 32.5 (4.31) | 32.8 (5.81) | 35.2 (1.19) |
| Memory condition | 20.3 (5.78)a,g | 15.3 (6.87)c,g | 26 (4.22) |
Means (SD) are shown.
a
p<0.05, vs. healthy subjects comparison.
b
p<0.01, vs. healthy subjects comparison.
c
p<0.001, vs. healthy subjects comparison.
d
Median score in normative data = -1.77.
e
These indexes do not have normative data available.
f
Median score in normative data: cured patients = −1.68 (35% of patients scored below −1.5 SD); naïve patients = −2.21 (50% of patients scored below −1.5 SD); healthy subjects = 0.14 (no patient scored below −1.5 SD).
g
Median percentile with test’s normative data: cured patients = 12.5 (40% of patients below 10th percentile); naïve patients = 4 (70% of patients below 10th percentile); healthy subjects = 50 (no patient below 10th percentile).
Note: LMW-R = Luria’s Memory Words Test-Revised.