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. 2013 Apr 4;8(4):e60411. doi: 10.1371/journal.pone.0060411

Figure 1. Generation of Ins1-luc BAC transgenic mice.

Figure 1

(A) Diagrammatic representation of the transgene. (B) Representative example of a PCR-positive individual for genotyping. Control: interleukin-2. (C) Luciferase activity in tissue lysates of male Ins1-luc BAC transgenic mice at 4 to 6 weeks of age (n = 3). RLU: relative light unit. (D) Tissue sections of Ins1-luc BAC transgenic mouse stained with anti-insulin antibody (Ins), anti-luciferase antibody (Luc), and diamidino-2-phenylindole (DAPI). Scale bars: 50 µm.