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Inhibition of myristoylation and palmitoylation by 2-HMA and 2-BPA. A549, HEK293, and SKOV3 cells were transfected using the wild type v3(Grx)-GFP fusion construct. 18 h after transfection, cells were treated with either 1% EtOH or 2-hydroxymyristate for 48 h or with 2-bromopalmitate for 24 h. GFP fluorescence was recorded using confocal microscopy. Scale bar = 20 μm. Ctrl, control.
