TABLE 4.

Neutralization ID₅₀ values obtained with pooled terminal bleed sera (week 55) before and after depletion

	ID50 in TZM-bl cells
	MN.3	SF162.LS
Group 1 undepleted	455	2305
Group 2 undepleted	2975	1015
Group 3 undepleted	13,545	4620
Group 1 depleted on gp120	115	30
Group 2 depleted on gp120	740	130
Group 3 depleted on gp120	280	105
Group 1 depleted on D368R	145	75
Group 2 depleted on D368R	1135	450
Group 3 depleted on D368R	1105	270
Group 1 depleted on BSA	490	1945
Group 2 depleted on BSA	2470	750
Group 3 depleted on BSA	11,735	3980

^a For groups 2 and 3, ID₅₀ values of the sera depleted on gp120 are considerably reduced relative to the same sera depleted on gp120 D368R. This is not the case for sera in group 1.