Figure 1.
Sequence alignment of the pore-lining helix of MscS-like channels, which have been electrophysiologically characterized. ecMscS from E. coli accession number (AN) P0C0S2 (15,16); MscSP from S. pomeroyi AN Q5LMR6 (4); MSC1 from C. reinhardtii AN EDP05899 (18); MscCG from Corynebacterium glutamicum AN NP_600492 (23); MscMJ and MscMJLR from Methanocaldococcus jannaschii ANs Q57634 and Q58543, respectively (26); TtMscS from Thermoanaerobacter tengcongensis AN NP_624283 (21) (∗personal communication, Irene Iscla, 2013); and MSL10 from Arabidopsis thaliana AN Q9LYG9 (27). Residue numbering corresponds to ecMscS sequence.